Unliganded Thyroid Hormone Receptor α Regulates Developmental Timing via Gene Repression in Xenopus tropicalis

Thyroid hormone (TH) receptor (TR) expression begins early in development in all vertebrates when circulating TH levels are absent or minimal, yet few developmental roles for unliganded TRs have been established. Unliganded TRs are expected to repress TH-response genes, increase tissue responsivity...

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Détails bibliographiques
Publié dans:Endocrinology
Auteurs principaux: Choi, Jinyoung, Suzuki, Ken-ichi T., Sakuma, Tetsushi, Shewade, Leena, Yamamoto, Takashi, Buchholz, Daniel R.
Format: Artigo
Langue:Inglês
Publié: Endocrine Society 2015
Sujets:
Thyroid-TRH-TSH
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298327/
https://ncbi.nlm.nih.gov/pubmed/25456067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1554
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