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Unliganded Thyroid Hormone Receptor α Controls Developmental Timing in Xenopus tropicalis

Thyroid hormone (T(3)) affects adult metabolism and postembryonic development in vertebrates. T(3) functions mainly via binding to its receptors (TRs) to regulate gene expression. There are 2 TR genes, TRα and TRβ, with TRα more ubiquitously expressed. During development, TRα expression appears earl...

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Bibliografske podrobnosti
izdano v:Endocrinology
Main Authors: Wen, Luan, Shi, Yun-Bo
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298314/
https://ncbi.nlm.nih.gov/pubmed/25456066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1439
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