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Unliganded Thyroid Hormone Receptor α Regulates Developmental Timing via Gene Repression in Xenopus tropicalis

Thyroid hormone (TH) receptor (TR) expression begins early in development in all vertebrates when circulating TH levels are absent or minimal, yet few developmental roles for unliganded TRs have been established. Unliganded TRs are expected to repress TH-response genes, increase tissue responsivity...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Choi, Jinyoung, Suzuki, Ken-ichi T., Sakuma, Tetsushi, Shewade, Leena, Yamamoto, Takashi, Buchholz, Daniel R.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298327/
https://ncbi.nlm.nih.gov/pubmed/25456067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1554
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