Unliganded Thyroid Hormone Receptor α Regulates Developmental Timing via Gene Repression in Xenopus tropicalis

Thyroid hormone (TH) receptor (TR) expression begins early in development in all vertebrates when circulating TH levels are absent or minimal, yet few developmental roles for unliganded TRs have been established. Unliganded TRs are expected to repress TH-response genes, increase tissue responsivity...

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Dades bibliogràfiques
Publicat a:Endocrinology
Autors principals: Choi, Jinyoung, Suzuki, Ken-ichi T., Sakuma, Tetsushi, Shewade, Leena, Yamamoto, Takashi, Buchholz, Daniel R.
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2015
Matèries:
Thyroid-TRH-TSH
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298327/
https://ncbi.nlm.nih.gov/pubmed/25456067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1554
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