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5″-Amino-5″-Deoxybutirosin, a Semisynthetic Analogue of Butirosin A: Antibacterial Activity In Vitro and in Mice

Aminodeoxybutirosin (AD-BTN), the 5″-amino-5″-deoxy derivative of butirosin (BTN), was synthesized to improve on the antibacterial activity of BTN by preventing bacterial enzymatic phosphorylation at the 5″ position. AD-BTN possesses the spectrum characteristic of BTN and gentamicin (GTM) and was ac...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Heifetz, C. L., Frey, C. A., Pearson, I. A., Sesnie, J. C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1976
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC429785/
https://ncbi.nlm.nih.gov/pubmed/62554
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