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5″-Amino-5″-Deoxybutirosin, a Semisynthetic Analogue of Butirosin A: Antibacterial Activity In Vitro and in Mice
Aminodeoxybutirosin (AD-BTN), the 5″-amino-5″-deoxy derivative of butirosin (BTN), was synthesized to improve on the antibacterial activity of BTN by preventing bacterial enzymatic phosphorylation at the 5″ position. AD-BTN possesses the spectrum characteristic of BTN and gentamicin (GTM) and was ac...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
1976
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC429785/ https://ncbi.nlm.nih.gov/pubmed/62554 |
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