5″-Amino-5″-Deoxybutirosin, a Semisynthetic Analogue of Butirosin A: Antibacterial Activity In Vitro and in Mice

Aminodeoxybutirosin (AD-BTN), the 5″-amino-5″-deoxy derivative of butirosin (BTN), was synthesized to improve on the antibacterial activity of BTN by preventing bacterial enzymatic phosphorylation at the 5″ position. AD-BTN possesses the spectrum characteristic of BTN and gentamicin (GTM) and was ac...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Heifetz, C. L., Frey, C. A., Pearson, I. A., Sesnie, J. C.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1976
Assuntos:	Pharmacology and Therapeutics
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429785/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/62554/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.10.3.543
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