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Human SLC4A11-C functions as a DIDS-stimulatable H(+)(OH(−)) permeation pathway: partial correction of R109H mutant transport

The SLC4A11 gene mutations cause a variety of genetic corneal diseases, including congenital hereditary endothelial dystrophy 2 (CHED2), Harboyan syndrome, some cases of Fuchs' endothelial dystrophy (FECD), and possibly familial keratoconus. Three NH(2)-terminal variants of the human SLC4A11 ge...

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Pubblicato in:Am J Physiol Cell Physiol
Autori principali: Kao, Liyo, Azimov, Rustam, Abuladze, Natalia, Newman, Debra, Kurtz, Ira
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297769/
https://ncbi.nlm.nih.gov/pubmed/25394471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00271.2014
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