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IL-2Rβ-dependent signaling and CD103 functionally cooperate to maintain tolerance in the gut mucosa

A network of mechanisms operates to maintain tolerance in the gut mucosa. Although CD103 marks many lymphoid cells within the gut, its direct functional role in intestinal tolerance is poorly understood. CD103 may be part of a redundant pathway as CD103(−/−) mice do not exhibit autoimmunity. To redu...

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Pubblicato in:J Immunol
Autori principali: Yuan, Xiaomei, Dee, Michael J., Altman, Norman H., Malek, Thomas R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297734/
https://ncbi.nlm.nih.gov/pubmed/25527788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400955
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