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The importance of regulatory T-cell heterogeneity in maintaining self-tolerance

CD4(+) Forkhead box protein 3 (Foxp3)(+) regulatory T cells (Tregs) are the major cell type that mediates dominant tolerance in the periphery. Over the past decade, extensive study of Tregs has revealed that these cells express substantial heterogeneity to maintain tolerance and regulate immune resp...

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Detalhes bibliográficos
Main Authors: Yuan, Xiaomei, Cheng, Guoyan, Malek, Thomas R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983566/
https://ncbi.nlm.nih.gov/pubmed/24712462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12163
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