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T cell tolerance and the multi-functional role of IL-2R signaling in T regulatory cells

Signaling through the interleukin-2 receptor (IL-2R) contributes to T-cell tolerance by controlling three important aspects of regulatory T-cell (Treg) biology. IL-2 is essential for thymic Treg development and regulates Treg homeostasis and suppressive function. Analogous to activated conventional...

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Main Authors: Cheng, Guoyan, Yu, Aixin, Malek, Thomas R.
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101713/
https://ncbi.nlm.nih.gov/pubmed/21488890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-065X.2011.01004.x
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