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Interleukin-2 receptor signaling is essential for the development of Klrg1(+) terminally differentiated T regulatory cells()

Thymic-derived natural T regulatory cells (nTregs) are characterized by functional and phenotypic heterogeneity. Recently, a small fraction of peripheral Tregs have been shown to express Klrg1, but it remains unclear the extent Klrg1 defines a unique Treg subset. Here we show that Klrg1(+) Tregs rep...

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Bibliographische Detailangaben
Hauptverfasser: Cheng, Guoyan, Yuan, Xiaomei, Tsai, Matthew S., Podack, Eckhard R., Yu, Aixin, Malek, Thomas R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411868/
https://ncbi.nlm.nih.gov/pubmed/22786769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103768
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