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Cellular and molecular determinants for the development of natural and induced regulatory T cells

Regulation of immune responses to self and foreign antigens is critically dependent on suppressive CD4(+) T cells characterized by expression of Foxp3. The large majority of regulatory T (Treg) cells develop in the thymus as a stable suppressive lineage. However, under the proper physiological condi...

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Detalhes bibliográficos
Main Authors: Yuan, Xiaomei, Malek, Thomas R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410644/
https://ncbi.nlm.nih.gov/pubmed/22659217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humimm.2012.05.010
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