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IL-2Rβ-dependent signaling and CD103 functionally cooperate to maintain tolerance in the gut mucosa

A network of mechanisms operates to maintain tolerance in the gut mucosa. Although CD103 marks many lymphoid cells within the gut, its direct functional role in intestinal tolerance is poorly understood. CD103 may be part of a redundant pathway as CD103(−/−) mice do not exhibit autoimmunity. To redu...

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Détails bibliographiques
Publié dans:J Immunol
Auteurs principaux: Yuan, Xiaomei, Dee, Michael J., Altman, Norman H., Malek, Thomas R.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297734/
https://ncbi.nlm.nih.gov/pubmed/25527788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400955
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