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Identifying actionable targets through integrative analyses of GEM model and human prostate cancer genomic profiling

Copy number alterations (CNAs) are among the most common molecular events in human prostate cancer genomes and are associated with worse prognosis. Identification of the oncogenic drivers within these CNAs is challenging due to the broad nature of these genomic gains or losses which can include larg...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Wanjala, Jackie, Taylor, Barry S, Chapinski, Caren, Hieronymus, Haley, Wongvipat, John, Chen, Yu, Nanjangud, Gouri J, Schultz, Nikolaus, Xie, Yingqiu, Liu, Shenji, Lu, Wenfu, Yang, Qing, Sander, Chris, Chen, Zhenbang, Sawyers, Charles L, Carver, Brett S
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297258/
https://ncbi.nlm.nih.gov/pubmed/25381262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-14-0542-T
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