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Loss of GM-CSF signalling in non-haematopoietic cells increases NSAID ileal injury
BACKGROUND: Administration of granulocyte-macrophage colony stimulating factor (GM-CSF) relieves symptoms in Crohn's disease (CD). It has been reported that reduced GM-CSF bioactivity is associated with more aggressive ileal behaviour and that GM-CSF-null mice exhibit ileal barrier dysfunction...
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| Publicado no: | Gut |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4296557/ https://ncbi.nlm.nih.gov/pubmed/20584783 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2009.203893 |
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