Developing an in vitro screening assay platform for evaluation of antifibrotic drugs using precision-cut liver slices

BACKGROUND: Precision-cut liver slices present different cell types of liver in a physiological context, and they have been explored as effective in vitro model systems to study liver fibrosis. Inducing fibrosis in the liver slices using toxicants like carbon tetrachloride is of less relevance to hu...

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Publicado en:Fibrogenesis Tissue Repair
Autores principales: Sadasivan, Satish Kumar, Siddaraju, Nethra, Khan, Khaiser Mehdi, Vasamsetti, Balamuralikrishna, Kumar, Nimisha R, Haridas, Vibha, Reddy, Madhusudhan B, Baggavalli, Somesh, Oommen, Anup M, Pralhada Rao, Raghavendra
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4296550/
https://ncbi.nlm.nih.gov/pubmed/25598841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13069-014-0017-2
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