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The Effect of Antifibrotic Drugs in Rat Precision-Cut Fibrotic Liver Slices

Two important signaling pathways in liver fibrosis are the PDGF- and TGFβ pathway and compounds inhibiting these pathways are currently developed as antifibrotic drugs. Testing antifibrotic drugs requires large numbers of animal experiments with high discomfort. Therefore, a method to study these dr...

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Autori principali: Westra, Inge M., Oosterhuis, Dorenda, Groothuis, Geny M. M., Olinga, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3995767/
https://ncbi.nlm.nih.gov/pubmed/24755660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095462
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