Murine Precision-cut Intestinal Slices as a Potential Screening Tool for Antifibrotic Drugs

BACKGROUND: Intestinal fibrosis is a hallmark of Crohn’s disease. Here, we investigated the impact of several putative antifibrotic compounds on the expression of fibrosis markers using murine precision-cut intestinal slices. METHODS: Murine precision-cut intestinal slices were cultured for 48 hours...

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Bibliografske podrobnosti
izdano v:Inflamm Bowel Dis
Main Authors: Iswandana, Raditya, Pham, Bao Tung, Suriguga, Su, Luangmonkong, Theerut, van Wijk, Louise A, Jansen, Yvette J M, Oosterhuis, Dorenda, Mutsaers, Henricus Antonius Maria, Olinga, Peter
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Basic Science Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7150673/
https://ncbi.nlm.nih.gov/pubmed/31943022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ibd/izz329
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