Developing an in vitro screening assay platform for evaluation of antifibrotic drugs using precision-cut liver slices

BACKGROUND: Precision-cut liver slices present different cell types of liver in a physiological context, and they have been explored as effective in vitro model systems to study liver fibrosis. Inducing fibrosis in the liver slices using toxicants like carbon tetrachloride is of less relevance to hu...

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Détails bibliographiques
Publié dans:Fibrogenesis Tissue Repair
Auteurs principaux: Sadasivan, Satish Kumar, Siddaraju, Nethra, Khan, Khaiser Mehdi, Vasamsetti, Balamuralikrishna, Kumar, Nimisha R, Haridas, Vibha, Reddy, Madhusudhan B, Baggavalli, Somesh, Oommen, Anup M, Pralhada Rao, Raghavendra
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4296550/
https://ncbi.nlm.nih.gov/pubmed/25598841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13069-014-0017-2
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