Transglutaminase factor XIII promotes arthritis through mechanisms linked to inflammation and bone erosion

Rheumatoid arthritis is a chronic inflammatory disease characterized by synovial hyperplasia, inflammatory cell infiltration, irreversible cartilage and bone destruction, and exuberant coagulation system activity within joint tissue. Here, we demonstrate that the coagulation transglutaminase, factor...

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Pubblicato in:Blood
Autori principali: Raghu, Harini, Cruz, Carolina, Rewerts, Cheryl L., Frederick, Malinda D., Thornton, Sherry, Mullins, Eric S., Schoenecker, Jonathan G., Degen, Jay L., Flick, Matthew J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2015
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Plenary Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4296006/
https://ncbi.nlm.nih.gov/pubmed/25336631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-08-594754
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