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Transglutaminase factor XIII promotes arthritis through mechanisms linked to inflammation and bone erosion

Rheumatoid arthritis is a chronic inflammatory disease characterized by synovial hyperplasia, inflammatory cell infiltration, irreversible cartilage and bone destruction, and exuberant coagulation system activity within joint tissue. Here, we demonstrate that the coagulation transglutaminase, factor...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Blood
Hauptverfasser: Raghu, Harini, Cruz, Carolina, Rewerts, Cheryl L., Frederick, Malinda D., Thornton, Sherry, Mullins, Eric S., Schoenecker, Jonathan G., Degen, Jay L., Flick, Matthew J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4296006/
https://ncbi.nlm.nih.gov/pubmed/25336631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-08-594754
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