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Transglutaminase factor XIII promotes arthritis through mechanisms linked to inflammation and bone erosion

Rheumatoid arthritis is a chronic inflammatory disease characterized by synovial hyperplasia, inflammatory cell infiltration, irreversible cartilage and bone destruction, and exuberant coagulation system activity within joint tissue. Here, we demonstrate that the coagulation transglutaminase, factor...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Raghu, Harini, Cruz, Carolina, Rewerts, Cheryl L., Frederick, Malinda D., Thornton, Sherry, Mullins, Eric S., Schoenecker, Jonathan G., Degen, Jay L., Flick, Matthew J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4296006/
https://ncbi.nlm.nih.gov/pubmed/25336631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-08-594754
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