Ranolazine inhibits Na(V)1.5-mediated breast cancer cell invasiveness and lung colonization

BACKGROUND: Na(V)1.5 voltage-gated sodium channels are abnormally expressed in breast tumours and their expression level is associated with metastatic occurrence and patients’ death. In breast cancer cells, Na(V)1.5 activity promotes the proteolytic degradation of the extracellular matrix and enhanc...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Driffort, Virginie, Gillet, Ludovic, Bon, Emeline, Marionneau-Lambot, Séverine, Oullier, Thibauld, Joulin, Virginie, Collin, Christine, Pagès, Jean-Christophe, Jourdan, Marie-Lise, Chevalier, Stéphan, Bougnoux, Philippe, Le Guennec, Jean-Yves, Besson, Pierre, Roger, Sébastien
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4295566/
https://ncbi.nlm.nih.gov/pubmed/25496128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-264
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados