SCN4B acts as a metastasis-suppressor gene preventing hyperactivation of cell migration in breast cancer

The development of metastases largely relies on the capacity of cancer cells to invade extracellular matrices (ECM) using two invasion modes termed ‘mesenchymal' and ‘amoeboid', with possible transitions between these modes. Here we show that the SCN4B gene, encoding for the β4 protein, in...

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Библиографические подробности
Опубликовано в: :Nat Commun
Главные авторы: Bon, Emeline, Driffort, Virginie, Gradek, Frédéric, Martinez-Caceres, Carlos, Anchelin, Monique, Pelegrin, Pablo, Cayuela, Maria-Luisa, Marionneau-Lambot, Séverine, Oullier, Thibauld, Guibon, Roseline, Fromont, Gaëlle, Gutierrez-Pajares, Jorge L., Domingo, Isabelle, Piver, Eric, Moreau, Alain, Burlaud-Gaillard, Julien, Frank, Philippe G., Chevalier, Stéphan, Besson, Pierre, Roger, Sébastien
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5150224/
https://ncbi.nlm.nih.gov/pubmed/27917859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13648
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