Impairment of Glioma Stem Cell Survival and Growth by a Novel Inhibitor for Survivin–Ran Protein Complex

PURPOSE: Glioblastoma multiforme (GBM) is a devastating disease. Recent studies suggest that the stem cell properties of GBM contribute to the development of therapy resistance. EXPERIMENTAL DESIGN: The expression of Survivin and Ran was evaluated by immunohistochemistry with GBM tissues, and quanti...

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Udgivet i:Clin Cancer Res
Main Authors: Guvenc, Hacer, Pavlyukov, Marat S., Joshi, Kaushal, Kurt, Habibe, Banasavadi-Siddegowda, Yeshavanth K., Mao, Ping, Hong, Christopher, Yamada, Ryosuke, Kwon, Chang-Hyuk, Bhasin, Deepak, Chettiar, Somsundaram, Kitange, Gaspar, Park, In-Hee, Sarkaria, Jann N., Li, Chenglong, Shakhparonov, Mihail I., Nakano, Ichiro
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4295559/
https://ncbi.nlm.nih.gov/pubmed/23251006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-0647
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