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Tumor-specific Activation of the c-JUN/MELK Pathway Regulates Glioma Stem Cell Growth in a p53-dependent Manner
Accumulated evidence suggests that glioma stem cells (GSCs) may contribute to therapy resistance in high grade glioma (HGG). Although recent studies have shown that the serine/threonine kinase MELK is abundantly expressed in various cancers, the function and mechanism of MELK remain elusive. Here, w...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4132653/ https://ncbi.nlm.nih.gov/pubmed/23339114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1322 |
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