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Prion protein (PrP) gene-knockout cell lines: insight into functions of the PrP

Elucidation of prion protein (PrP) functions is crucial to fully understand prion diseases. A major approach to studying PrP functions is the use of PrP gene-knockout (Prnp(−/−)) mice. So far, six types of Prnp(−/−) mice have been generated, demonstrating the promiscuous functions of PrP. Recently,...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Sakudo, Akikazu, Onodera, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4295555/
https://ncbi.nlm.nih.gov/pubmed/25642423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2014.00075
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