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The RASSF1A Tumor Suppressor Regulates XPA-Mediated DNA Repair

RASSF1A may be the most frequently inactivated tumor suppressor identified in human cancer so far. It is a proapoptotic Ras effector and plays an important role in the apoptotic DNA damage response (DDR). We now show that in addition to DDR regulation, RASSF1A also plays a key role in the DNA repair...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Donninger, Howard, Clark, Jennifer, Rinaldo, Francesca, Nelson, Nicholas, Barnoud, Thibaut, Schmidt, M. Lee, Hobbing, Katharine R., Vos, Michele D., Sils, Brian, Clark, Geoffrey J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4295385/
https://ncbi.nlm.nih.gov/pubmed/25368379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00202-14
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