The RASSF1A Tumor Suppressor Regulates XPA-Mediated DNA Repair

RASSF1A may be the most frequently inactivated tumor suppressor identified in human cancer so far. It is a proapoptotic Ras effector and plays an important role in the apoptotic DNA damage response (DDR). We now show that in addition to DDR regulation, RASSF1A also plays a key role in the DNA repair...

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Bibliografiset tiedot
Julkaisussa:Mol Cell Biol
Päätekijät: Donninger, Howard, Clark, Jennifer, Rinaldo, Francesca, Nelson, Nicholas, Barnoud, Thibaut, Schmidt, M. Lee, Hobbing, Katharine R., Vos, Michele D., Sils, Brian, Clark, Geoffrey J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2014
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Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4295385/
https://ncbi.nlm.nih.gov/pubmed/25368379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00202-14
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