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The Ras Effector RASSF2 Controls the PAR-4 Tumor Suppressor
RASSF2 is a novel proapoptotic effector of K-Ras. Inhibition of RASSF2 expression enhances the transforming effects of K-Ras, and epigenetic inactivation of RASSF2 is frequently detected in mutant Ras-containing primary tumors. Thus, RASSF2 is implicated as a tumor suppressor whose inactivation faci...
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| Auteurs principaux: | , , , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology (ASM)
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2876522/ https://ncbi.nlm.nih.gov/pubmed/20368356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00208-09 |
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