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RASSF1A deficiency enhances RAS driven lung tumorigenesis
Mutant K-RAS has been shown to have both tumor promoting and suppressing functions and growing evidence suggests that the RASSF family of tumor suppressors can act as RAS apoptosis and senescences effectors. It has been hypothesized that inactivation of the RASSF1A tumor suppressor facilitates K-RAS...
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| Publié dans: | Cancer Res |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5955812/ https://ncbi.nlm.nih.gov/pubmed/29735543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-2466 |
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