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A porcine model system of BRCA1 driven breast cancer
BRCA1 is a breast and ovarian tumor suppressor. Hereditary mutations in BRCA1 result in a predisposition to breast cancer, and BRCA1 expression is down-regulated in ~30% of sporadic cases. The function of BRCA1 remains poorly understood, but it appears to play an important role in DNA repair and the...
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Publicado no: | Front Genet |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Frontiers Media S.A.
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4548227/ https://ncbi.nlm.nih.gov/pubmed/26379698 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2015.00269 |
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