Substrate Trapping Proteomics Reveals Targets of the βTrCP2/FBXW11 Ubiquitin Ligase

Defining the full complement of substrates for each ubiquitin ligase remains an important challenge. Improvements in mass spectrometry instrumentation and computation and in protein biochemistry methods have resulted in several new methods for ubiquitin ligase substrate identification. Here we used...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Kim, Tai Young, Siesser, Priscila F., Rossman, Kent L., Goldfarb, Dennis, Mackinnon, Kathryn, Yan, Feng, Yi, XianHua, MacCoss, Michael J., Moon, Randall T., Der, Channing J., Major, Michael B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4295375/
https://ncbi.nlm.nih.gov/pubmed/25332235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00857-14
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