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Variants of uncertain significance in BRCA: a harbinger of ethical and policy issues to come?

After two decades of genetic testing and research, the BRCA1 and BRCA2 genes are two of the most well-characterized genes in the human genome. As a result, variants of uncertain significance (VUS; also called variants of unknown significance) are reported less frequently than for genes that have bee...

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Detalhes bibliográficos
Publicado no:Genome Med
Main Authors: Cheon, Jae Yeon, Mozersky, Jessica, Cook-Deegan, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4295298/
https://ncbi.nlm.nih.gov/pubmed/25593598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-014-0121-3
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