Clinically Applicable Models to Characterize BRCA1 and BRCA2 Variants of Uncertain Significance

PURPOSE: Twenty percent of individuals with a strong family and/or personal history of breast and ovarian cancer carry a deleterious mutation in BRCA1 or BRCA2. Identification of mutations in these genes is extremely beneficial for patients pursuing risk reduction strategies. Approximately 7% of ind...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Spearman, Andrew D., Sweet, Kevin, Zhou, Xiao-Ping, McLennan, Jane, Couch, Fergus J., Toland, Amanda Ewart
Format: Artigo
Jezik:Inglês
Izdano: American Society of Clinical Oncology 2008
Teme:
Genetic Testing for Cancer
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651073/
https://ncbi.nlm.nih.gov/pubmed/18824701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2008.17.8228
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki