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Clinically Applicable Models to Characterize BRCA1 and BRCA2 Variants of Uncertain Significance
PURPOSE: Twenty percent of individuals with a strong family and/or personal history of breast and ovarian cancer carry a deleterious mutation in BRCA1 or BRCA2. Identification of mutations in these genes is extremely beneficial for patients pursuing risk reduction strategies. Approximately 7% of ind...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Clinical Oncology
2008
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2651073/ https://ncbi.nlm.nih.gov/pubmed/18824701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2008.17.8228 |
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