INPP5E interacts with AURKA, linking phosphoinositide signaling to primary cilium stability

Mutations in inositol polyphosphate 5-phosphatase E (INPP5E) cause the ciliopathies known as Joubert and MORM syndromes; however, the role of INPP5E in ciliary biology is not well understood. Here, we describe an interaction between INPP5E and AURKA, a centrosomal kinase that regulates mitosis and c...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Plotnikova, Olga V., Seo, Seongjin, Cottle, Denny L., Conduit, Sarah, Hakim, Sandra, Dyson, Jennifer M., Mitchell, Christina A., Smyth, Ian M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294778/
https://ncbi.nlm.nih.gov/pubmed/25395580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.161323
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