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INPP5E interacts with AURKA, linking phosphoinositide signaling to primary cilium stability
Mutations in inositol polyphosphate 5-phosphatase E (INPP5E) cause the ciliopathies known as Joubert and MORM syndromes; however, the role of INPP5E in ciliary biology is not well understood. Here, we describe an interaction between INPP5E and AURKA, a centrosomal kinase that regulates mitosis and c...
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| Udgivet i: | J Cell Sci |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Company of Biologists
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4294778/ https://ncbi.nlm.nih.gov/pubmed/25395580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.161323 |
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