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Association of the circadian factor Period 2 to p53 influences p53's function in DNA-damage signaling
Circadian period proteins influence cell division and death by associating with checkpoint components, although their mode of regulation has not been firmly established. hPer2 forms a trimeric complex with hp53 and its negative regulator Mdm2. In unstressed cells, this association leads to increased...
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| Veröffentlicht in: | Mol Biol Cell |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The American Society for Cell Biology
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4294682/ https://ncbi.nlm.nih.gov/pubmed/25411341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-05-0994 |
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