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Association of the circadian factor Period 2 to p53 influences p53's function in DNA-damage signaling

Circadian period proteins influence cell division and death by associating with checkpoint components, although their mode of regulation has not been firmly established. hPer2 forms a trimeric complex with hp53 and its negative regulator Mdm2. In unstressed cells, this association leads to increased...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Gotoh, Tetsuya, Vila-Caballer, Marian, Liu, Jingjing, Schiffhauer, Samuel, Finkielstein, Carla V.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294682/
https://ncbi.nlm.nih.gov/pubmed/25411341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-05-0994
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