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Model-driven experimental approach reveals the complex regulatory distribution of p53 by the circadian factor Period 2
The circadian clock and cell cycle networks are interlocked on the molecular level, with the core clock loop exerting a multilevel regulatory role over cell cycle components. This is particularly relevant to the circadian factor Period 2 (Per2), which modulates the stability of the tumor suppressor...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5127372/ https://ncbi.nlm.nih.gov/pubmed/27834218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1607984113 |
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