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The circadian factor Period 2 modulates p53 stability and transcriptional activity in unstressed cells

Human Period 2 (hPer2) is a transcriptional regulator at the core of the circadian clock mechanism that is responsible for generating the negative feedback loop that sustains the clock. Its relevance to human disease is underlined by alterations in its function that affect numerous biochemical and p...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Gotoh, Tetsuya, Vila-Caballer, Marian, Santos, Carlo S., Liu, Jingjing, Yang, Jianhua, Finkielstein, Carla V.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4230596/
https://ncbi.nlm.nih.gov/pubmed/25103245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-05-0993
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