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Axonal amyloid precursor protein and its fragments undergo somatodendritic endocytosis and processing
Deposition of potentially neurotoxic Aβ fragments derived from amyloid precursor protein (APP) at synapses may be a key contributor to Alzheimer's disease. However, the location(s) of proteolytic processing and subsequent secretion of APP fragments from highly compartmentalized, euploid neurons...
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| Publicado en: | Mol Biol Cell |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The American Society for Cell Biology
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4294669/ https://ncbi.nlm.nih.gov/pubmed/25392299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-06-1049 |
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