Relaxin Activates Peroxisome Proliferator-activated Receptor γ (PPARγ) through a Pathway Involving PPARγ Coactivator 1α (PGC1α)

Relaxin activation of its receptor RXFP1 triggers multiple signaling pathways. Previously, we have shown that relaxin activates PPARγ transcriptional activity in a ligand-independent manner, but the mechanism for this effect was unknown. In this study, we examined the signaling pathways of downstrea...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Singh, Sudhir, Simpson, Ronda L., Bennett, Robert G.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2015
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294522/
https://ncbi.nlm.nih.gov/pubmed/25389293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.589325
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