Peroxisome Proliferator-activated Receptor-γ Coactivator 1-α (PGC1α) Protects against Experimental Murine Colitis

Peroxisome proliferator-activated receptor-γ coactivator 1-α (PGC1α) is the primary regulator of mitochondrial biogenesis and was recently found to be highly expressed within the intestinal epithelium. PGC1α is decreased in the intestinal epithelium of patients with inflammatory bowel disease, but i...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Cunningham, Kellie E., Vincent, Garret, Sodhi, Chhinder P., Novak, Elizabeth A., Ranganathan, Sarangarajan, Egan, Charlotte E., Stolz, Donna Beer, Rogers, Matthew B., Firek, Brian, Morowitz, Michael J., Gittes, George K., Zuckerbraun, Brian S., Hackam, David J., Mollen, Kevin P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2016
Schlagworte:
Molecular Bases of Disease
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858969/
https://ncbi.nlm.nih.gov/pubmed/26969166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.688812
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