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ABCA1 and nascent HDL biogenesis

ABCA1 mediates the secretion of cellular free cholesterol and phospholipids to an extracellular acceptor, apolipoprotein AI, to form nascent high-density lipoprotein (HDL). Thus, ABCA1 is a key molecule in cholesterol homeostasis. Functional studies of certain Tangier disease mutations demonstrate t...

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Detalles Bibliográficos
Publicado en:Biofactors
Main Authors: Wang, Shuhui, Smith, Jonathan D.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294467/
https://ncbi.nlm.nih.gov/pubmed/25359426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/biof.1187
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