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N-terminal mutation of apoA-I and interaction with ABCA1 reveal mechanisms of nascent HDL biogenesis

ApoA-I and ABCA1 play important roles in nascent HDL (nHDL) biogenesis, the first step in the pathway of reverse cholesterol transport that protects against cardiovascular disease. On the basis of the crystal structure of a C-terminally truncated form of apoA-I[Δ(185-243)] determined in our laborato...

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Dades bibliogràfiques
Publicat a:J Lipid Res
Autors principals: Liu, Minjing, Mei, Xiaohu, Herscovitz, Haya, Atkinson, David
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314262/
https://ncbi.nlm.nih.gov/pubmed/30249788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M084376
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