Noxa upregulation by oncogenic activation of MEK/ERK through CREB promotes autophagy in human melanoma cells

Reduction in the expression of the anti-survival BH3-only proteins PUMA and Bim is associated with the pathogenesis of melanoma. However, we have found that the expression of the other BH3-only protein Noxa is commonly upregulated in melanoma cells, and that this is driven by oncogenic activation of...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Liu, Yi Lun, Lai, Fritz, Wilmott, James S., Yan, Xu Guang, Liu, Xiao Ying, Luan, Qi, Guo, Su Tang, Jiang, Chen Chen, Tseng, Hsin-Yi, Scolyer, Richard A., Jin, Lei, Zhang, Xu Dong
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2014
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294377/
https://ncbi.nlm.nih.gov/pubmed/25365078
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars