Mechanisms of Protection against Clostridium difficile Infection by the Monoclonal Antitoxin Antibodies Actoxumab and Bezlotoxumab

Clostridium difficile infection (CDI) represents the most prevalent cause of antibiotic-associated gastrointestinal infections in health care facilities in the developed world. Disease symptoms are caused by the two homologous exotoxins, TcdA and TcdB. Standard therapy for CDI involves administratio...

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Detalles Bibliográficos
Publicado en:Infect Immun
Autores principales: Yang, Zhiyong, Ramsey, Jeremy, Hamza, Therwa, Zhang, Yongrong, Li, Shan, Yfantis, Harris G., Lee, Dong, Hernandez, Lorraine D., Seghezzi, Wolfgang, Furneisen, Jamie M., Davis, Nicole M., Therien, Alex G., Feng, Hanping
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2015
Materias:
Bacterial Infections
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294251/
https://ncbi.nlm.nih.gov/pubmed/25486992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02897-14
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