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Modelling the time course of antimalarial parasite killing: a tour of animal and human models, translation and challenges

Malaria remains a global public health concern and current treatment options are suboptimal in some clinical settings. For effective chemotherapy, antimalarial drug concentrations must be sufficient to remove completely all of the parasites in the infected host. Optimized dosing therefore requires a...

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Bibliografiske detaljer
Udgivet i:Br J Clin Pharmacol
Main Authors: Patel, Kashyap, Simpson, Julie A, Batty, Kevin T, Zaloumis, Sophie, Kirkpatrick, Carl M
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294080/
https://ncbi.nlm.nih.gov/pubmed/24251882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12288
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