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Modelling the time course of antimalarial parasite killing: a tour of animal and human models, translation and challenges

Malaria remains a global public health concern and current treatment options are suboptimal in some clinical settings. For effective chemotherapy, antimalarial drug concentrations must be sufficient to remove completely all of the parasites in the infected host. Optimized dosing therefore requires a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Br J Clin Pharmacol
Hauptverfasser: Patel, Kashyap, Simpson, Julie A, Batty, Kevin T, Zaloumis, Sophie, Kirkpatrick, Carl M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294080/
https://ncbi.nlm.nih.gov/pubmed/24251882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12288
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