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Modelling the time course of antimalarial parasite killing: a tour of animal and human models, translation and challenges

Malaria remains a global public health concern and current treatment options are suboptimal in some clinical settings. For effective chemotherapy, antimalarial drug concentrations must be sufficient to remove completely all of the parasites in the infected host. Optimized dosing therefore requires a...

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Publicat a:Br J Clin Pharmacol
Autors principals: Patel, Kashyap, Simpson, Julie A, Batty, Kevin T, Zaloumis, Sophie, Kirkpatrick, Carl M
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294080/
https://ncbi.nlm.nih.gov/pubmed/24251882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12288
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