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Modelling the time course of antimalarial parasite killing: a tour of animal and human models, translation and challenges

Malaria remains a global public health concern and current treatment options are suboptimal in some clinical settings. For effective chemotherapy, antimalarial drug concentrations must be sufficient to remove completely all of the parasites in the infected host. Optimized dosing therefore requires a...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Patel, Kashyap, Simpson, Julie A, Batty, Kevin T, Zaloumis, Sophie, Kirkpatrick, Carl M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294080/
https://ncbi.nlm.nih.gov/pubmed/24251882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12288
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